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DeCS
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Descriptor English:
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Genes, myc
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Descriptor Spanish:
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Genes myc
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Descriptor Portuguese:
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Genes myc
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Synonyms English:
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c-myc Genes
L-myc Genes
myc Genes
N-myc Genes
v-myc Genes
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Tree Number:
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G05.360.340.024.340.375.500.791.420
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Definition English:
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Family of retrovirus-associated DNA sequences (myc) originally isolated from an avian myelocytomatosis virus. The proto-oncogene myc (c-myc) codes for a nuclear protein which is involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Truncation of the first exon, which appears to regulate c-myc expression, is crucial for tumorigenicity. The human c-myc gene is located at 8q24 on the long arm of chromosome 8. |
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Indexing Annotation English:
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myc stands for "MYeloCytomatosis"
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See Related English:
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Oncogene Protein p55(v-myc)
Proto-Oncogene Proteins c-myc
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History Note English:
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91; was MYC GENES see ONCOGENES 1985-90
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Allowable Qualifiers English:
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Record Number:
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28956
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Unique Identifier:
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D016259
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Occurrence in VHL:
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Similar:
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DeCS CID-10 SciELO LILACS LIS
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